MusclePharm has taken your typical nitric oxide product and upped the ante. The beginning was simple: Their science team turned to superior ingredients, which naturally leads to superior results and a more effective finished product.

By using Agmatine Sulfate, MusclePharm has utilized the "Super Arginine" to take your pumps to explosive new levels.

Although Agmatine inhibits some NOS Synthase (the enzyme that synthesizes nitric oxide), it both enhances and increases the levels and expression of endogenous nitric oxide Synthase (eNOS). You're left with shirt-splitting pumps that help take your workouts skyward. You've experienced pumps. But not these pumps. "Super Arginine"-loaded Hybrid N.O. delivers.

GlyoCarn, a scientifically-researched nitric oxide booster, encourages blood flow throughout the muscles. In fact, super-powerful GlyoCarn is one of the only ingredients suggested to increase nitric oxide levels in the human bloodstream. Its considerable list of benefits includes antioxidant activity, decreasing levels of MDA (malondialdehyde) in the post exercise phase, increased blood flow and enhanced ATP production. All in all, it helps you achieve better results during high-intensity exercise.*

Studies suggest that along with numerous other health benefits, the combination of Hawthorne Berry and Beet Root yields a higher level of nitric oxide production and exercise tolerance. Studies also have suggested that, together, they immediately produce nitric oxide as well as provide a sustained release of the nutrient over the course of about one hour. Hawthorne Berry and Beet Root also foster a steady rise in plasma nitrates and when broken down, these yield extra Nitric Oxide. They also lead to higher levels of plasma nitrite and nitrate, which further increase systemic Nitric Oxide bioavailability. Along with higher exercise tolerance and health promoting benefits, get ready for a Nitric Oxide pump unmatched by other supplements.*

But MusclePharm didn't stop there. They fully deploy the range of benefits of the nutrient Citrulline Malate. This extra step creates the complete nitric oxide product.

Scientifically, Citrulline Malate is used to synthesize L-arginine. This produces a recycling effect, and L-citrulline becomes nitric oxide through the L-Arginine. This process amplifies the effectiveness of the ingredients Glycocarn and Agmatine, which support improved aerobic performance and capacity by increasing the rate of oxidative ATP production during exercise. Post-exercise, it promotes an increased rate of phosphocreatine production for more effective recovery. CM may also decrease soreness in the gym by increasing rates of clearance of lactate and ammonia after exercise. At the same time, this buffers acidosis. Better recovery and decreased soreness supports size and strength gains. In huge ways. Those massive pumps from Hybrid N.O. pave the way to massive gains.*

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Agmatine: Agmatine inhibits nitric oxide synthase, which prevents the toxic effects associated with nitric oxide synthesis. Part of this is the release of peptide hormones that play an important role during the cell proliferation process. Agmatine also supports better vasodilation. In fact, it has been suggested to contain numerous systemic vasodilatory effects. In addition, agmatine is a powerful antioxidant. Further benefits include increased glomerular filtration rate and insulin release from the pancreas, along with modulation of gastric function.*

GlycoCarn: Known as glycine propionyl-L-carnitine, GlyoCarn is not only a glucogenic amino acid but is also crucial in the formation of creatine. The strong vasodilatory effects of nitric oxide have recently been suggested to increase nitric oxide production, as well as support increased peak power while reducing lactic acid buildup.*

Citruline Malate: A mixture of citrulline and malate, the citrulline involved allows the detoxification of ammonia. Malate is a key controller of aerobic ATP production rates. Combined, these two promote immense benefits. Active individuals may enjoy added energy production in aerobic exercise and decreased muscle soreness.*

Hawthorne Berry: Hawthorne Berry is an extract that has been around for centuries - it's one of the oldest natural wellness herbal plants used in Europe. Hawthorne benefits the circulatory system, promoting healthy flow of blood throughout the body.* This is a benefit athletes especially can appreciate.

Beet Root: A vegetable abundant in nitrates, Beet Root's dietary nitrate is reduced to bioactive nitrite NO2. It is then reduced further to nitric oxide as it is consumed. The result is increased plasma NO2. Dietary Beet Root supplementation may also help reduce muscle ATP turnover rate when you are under a heavy workload. Beet Root demonstrates potential to enhance exercise tolerance during lengthy endurance sessions.*