Creatine HSC™ from AST Sports Science
How to Pump Over 87% More Muscle Building Creatine into Your Muscles . . . and
Bio-Energetically Fuel the Phospho-Creatine Cycle for Sustained and Continual
Muscle Growth Over 247% Greater Than Creatine Monohydrate!
AST Sports
Science is networking with leading research groups around the world to deliver you
state-of-the-art creatine compounds that are more effective, work better and produce
results that the cheap creatine supplements can't come close to. Enter...
Creatine HSC™, the Hyper-Saturation Creatine Complex
The Problem . . .
We all know creatine monohydrate
works! You take it - you get bigger and you get stronger. You feel good, you feel
big, and you feel strong. You can knock out more and more reps with heavier and heavier
weights. It's great stuff - at least for the first month or so. Then what happens?
Bam! You hit that wall. The weights aren't moving up like they did at first. That
pump just doesn't seem quite as full as it use to. You know what I mean. This is
called diminished creatine efficacy. It happens to everyone who relies on simple creatine
monohydrate for the their creatine saturation needs.
The Solution . . .
One of the fundamental missions at
AST Sports Science is to foster a greater understanding into the dynamics of muscle
anabolism through nutritional intervention.
Creatine HSC™ takes the science of creatine supplementation even
further. New Creatine HSC™ is designed to create a more efficient and congruent atmosphere
to increase creatine uptake and utilization within the muscle cell by effectively
manipulating the intricate metabolic pathways of the phospho-creatine cycle.
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63-0351 |
AST
Creatine HSC, Lemon Squeeze
Discontinued by Manufacturer
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4 lb. |
Not available for sale |
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63-0352 |
AST
Creatine HSC, Juicy Grape
Discontinued by Manufacturer
|
4 lb. |
Not available for sale |
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Creatine
HSC's scientifically based creatine formula utilizes an advanced substrate
understanding to enhance the biological mechanisms of creatine metabolism. Creatine HSC™
maximizes the integration of creatine carrier sub-pathways and bioenergetic mediation to
effectively increase muscle cell creatine uptake, retention and creatine/ATP turnover.
Creatine HSC's innovative Hyper-Saturation Creatine
Complex incorporates pure HPLC creatine monohydrate with an integrated
bio-energetic ATP support system, a dual-phosphate / taurine matrix, unique sodium /
creatine mediators and DGC™ (high-glycemic-index dextrorotatory glucose crystals) to
help facilitate a desired creatine Hyper-Saturation effect. Through
this Hyper-Saturation effect, Creatine HSC™ delivers over
87% more creatine to your muscles than creatine monohydrate alone. And
it doesn't stop there . . .
Integrated ATP Support System
ATP Support System - AST Sports Science is currently
researching the bio-energetic complexities of the phospho-creatine cycle in order to gain
a better understanding of the co-interactions with relation to creatine / ATP synthesis.
These important intermediaries are key to increasing the intensity and duration of
creatine's muscle building effects. By providing these essential intermediate
substrates, Creatine HSC™ fuels a micro-cellular environment prime for continued
creatine/ATP turnover.
This permits creatine's potential as a fuel and a buffer for
ATP and as a contributor to cell hyper-hydration, protein accrual and muscular
growth. Creatine HSC™ provides the necessary micro-nutrients that take advantage of
creatine's site-specific substrate activity. By providing these bio-energetic
nutrients responsible for sustained creatine/ATP turnover, Creatine HSC™ delivers continual
dynamic muscle performance increases month after month after month.
Sodium-Creatine Mediators
Sodium-Creatine Mediators - Unknown to but a few resourceful researchers,
creatine uptake by the muscle cell
is sodium dependent - sodium is required for proper muscle-creatine delivery
and utilization. Providing the proper intra / extra-cellular creatine-sodium chemical
gradient is crucial to hyper creatine transport - getting more
creatine in the muscle than normally allowed under ordinary cellular-metabolic states.
Creatine HSC™ stimulates sodium-creatine cotransport by increasing the transmembrane
sodium concentration gradient. This increased sodium flow into the cell allows a
thermodynamic creatine attatchment to hitch-a-ride in with the
sodium. Creatine HSC™ provides a precise sodium requirement to increase cellular creatine
accumulation through cross-membrane sodium transport. Another first in the industry.
Dual-Phosphate / Taurine Matrix
Dual-Phosphate / Taurine Matrix - Creatine HSC™ integrates a precise
sodium-potassium phosphate combination along with HPLC Taurine for increased muscle cell
hydration and insulin-like mediation for creatine transport to promote an optimum
cellular medium for accelerated muscle growth. Controlled studies have demonstrated
Taurine's potent insulin-like characteristics and have also shown insulin
potentiating attributes as well. This dual mimic-potentiate ability may foster an even
greater net effect in insulin mediated creatine transport. Numerous studies are indicating
the more creatine that can be driven into the muscle cell, the more potential for
substantial lean mass accumulation.
Spiking Insulin!
DGC™ - Creatine HSC™ incorporates new high-glycemic-index Dextrorotatory
Glucose Crystals. This new glucose component helps mediate a significant increase in
creatine uptake and retention by having a sharp impact on serum insulin levels. This
insulin spike mediates a hyper uptake of
creatine into the muscle cell. DGC provides this insulin medium without the overly sweet
sensation other insulin spiking methods produce. Not only does Creatine HSC™ redefine the
science of creatine supplementation, but it now provides a refreshing way to do it.
Two Muscle-Quenching Flavors!
New Creatine HSC™ comes in two awesome and refreshing flavors - Juicy Grape
and Lemon Squeeze - in 4 pound (41 servings) containers. You just scoop it into a glass, add cold
water and stir. Creatine HSC™ mixes instantly into a great tasting, very refreshing and
potent muscle-building drink. It doesn't load you down or weigh heavy on your
stomach. Creatine HSC™ is simple to use and very effective.
Creatine HSC™ is a breakthrough supplement with a unique precision
Hyper-Saturation" formula that integrates the absolute latest in creatine
research, delivering you the most scientifically advanced creatine formula available to
help you build lean muscle and strength faster. Creatine HSC™ is defining a new era in
creatine effectiveness. Creatine HSC™ will change the way you think about fast muscle
growth!
Recommended Use: There is a 5 day loading phase: Take 1 serving 4 times a day. After 5 days you
reduce your intake to 1 or 2 servings per day.
Servings per container: 41
Serving Size: 1 scoop
Per serving:
- Calories: 136
- Protein: 0
- Carbohydrates: 34 g
- Fat: 0 g
- Micronized Creatine: 5 g
- Taurine: 1 g
References:
1. Carbohydrate ingestion augments skeletal muscle creatine
accumulation during creatine supplementation in humans. Am J Physiol 1996
Nov;271(5 Pt 1): E821-E826
2. Carbohydrate ingestion augments creatine retention during
creatine feeding in humans. Acct Physiol Scand 1996 Oct;158(2): 195-202
3. The utilization of creatine and its analogues by cytosolic
and mitochondrial creatine kinase. Biochim Biophys Acct 1996
Jun 13;1274(3):119-128
4. On the possible pharmacological role of UDP-glucose on some
muscular metabolites. Farmaco [Sci] 1984 Mar;39(3):246-254
5. Regulation of Ca2+ transport by insulin and
taurine. Interaction at the level of the Na(+)-Ca2+ exchanger. Adv Exp Med
Biol. 1996 Jan 1; 403: 551-560
6. Interstitial fluid concentrations of glycerol, glucose, and amino
acids in human quadricep muscle and adipose tissue. Evidence for significant lipolysis in
skeletal muscle. J Clin Invest. 1995 Jul 1; 96(1): 370-377
7. Plasma and platelet taurine are reduced in subjects with
insulin-dependent diabetes mellitus: effects of taurine supplementation. Am J
Clin Nutr. 1995 May 1; 61(5): 1115-1119
8. Does taurine bind to the insulin binding site of the insulin receptor?
Prog Clin Biol Res. 1990 Jan 1; 351: 95-102
9. Insulin-like activity of taurine. Adv Exp Med Biol. 1987
Jan 1; 217: 217-226
10. Potentiation of the actions of insulin by taurine. Can J
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11. Stimulation of muscle protein synthesis by long-term insulin infusion
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12. Physiologic hyperinsulinemia stimulates protein synthesis and
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Invest. 1995 Feb 1; 95(2): 811-819
13. Glucose and amino acid transport in human peripheral lymphocytes. Biochem
Soc Trans. 1994 Aug 1; 22(3): 269S
14. Effect of insulin on system A amino acid transport in human skeletal
muscle. J Clin Invest. 1993 Feb 1; 91(2): 514-521
15. Regulation by insulin of muscle protein metabolism during sepsis and
other catabolic conditions. Nutrition. 1992 Nov 1; 8(6): 434-439
16. Characterization of the adenosine receptor modulating insulin action
in rat skeletal muscle. Eur J Pharmacol. 1992 Jun 5; 226(2): 121-128
17. Effect of insulin on protein synthesis and degradation in skeletal
muscle after exercise. Am J Physiol. 1990 Jan 1; 258(1 Pt 1): E92-E97
18. Effect of hormonal and substrate backgrounds on cell membrane
function in normal males. J Appl Physiol. 1987 Sep 1; 63(3): 1107-1113
19. A transient increase in amino acid transport modulated by insulin in
differentiating muscle cells. J Cell Physiol. 1979 Feb 1; 98(2): 279-282
20. Signaling elements involved in amino acid transport responses to
altered muscle cell volume. FASEB J. 1997 Nov; 11(13): 1111-1117
21. Effects of insulin and exercise on amino acid transport in rat
skeletal muscle. Am J Physiol. 1994 Feb 1; 266(2 Pt 1): C524-C530
22. A multichannel transporter for glucose and amino acid transport. Fiziol
Zh SSSR Im I M Sechenova. 1992 Aug 1; 78(8): 84-92
23. Amino acid transport System L in muscle cells: biochemical properties
and its relation to protein synthesis. Biochim Biophys Acta. 1992 Jul 8;
1108(1): 1-7
24. The regulation of total creatine content in a myoblast cell line. Mol
Cell Biochem. 1996 May 24; 158(2): 179-188
25. The cloning and expression of a human creatine transporter. Biochem
Biophys Res Commun. 1994 Oct 14; 204(1): 419-427
26. Regulation of intracellular creatine in erythrocytes and myoblasts:
influence of uraemia and inhibition of Na,K-ATPase. Cell Biochem Funct. 1994
Jun 1; 12(2): 99-106
